Relationality is embedded in our daily lives. How we relate to one another conditions how we see ourselves and how we are seen. This virtual Public Lecture, based on the current Review of International Studies Special Issue (Volume 48 - Special Issue 5 - December 2022) on Pluriversal Relationality, addresses two challenges. First, what happens if we conceive relationality in a manner that ontologically begins by assuming interconnection as prior to the existence of entities. Second, it seeks to pluralize the sources of relational thinking in International Relations (IR) by showcasing how different cosmological traditions in the Americas, Asia and Australia view relationality. By highlighting a spectrum of relational engagement, it raises important questions about the way the various knowledge frames in IR are acknowledged, legitimised, limited, and reproduced and opens up the possibility of “doing IR differently”.